Stéfan Halbherr is one of five founders of the start-up company InnoMedica and has led the Research and Development department since the beginning 4 years ago. He studied biochemistry and immunology and holds a PhD degree from the University of Berne (Switzerland).
With a dedicated team and a 22-people-strong company he aims at bridging the gap between innovative medicine and patient’s needs. He developed a unique industrial scale GMP manufacturing process for ultra-small liposomes with novel biological properties.
This process enabled the research of pipeline products that today cover the areas of nano-chemotherapy and image guided surgery in oncology, neurodegenerative diseases, and bacteriology. With the first product Talidox moving into phase 1 testing a major milestone has been achieved.
Liposome pipeline addressing unmet medical needs in oncology, imaging, and neurodegeneration
Ultra-small liposomes of 30nm in size give rise to unknown pharmacological effects. Talidox (Targeted Liposomal Doxorubicin) accumulates chemotherapeutic drug in cancer tissue and minimizes its side effects. Using the nano-shuttle, near-infrared dye is specifically transported to tumors and can assist during fluorescence-guided surgery. Talineuren (Targeted Liposomal Neuroregenerator) delivers neuroprotective GM1 ganglioside to the brain after oral intake, thereby e.g. elevating dopamine levels in the striatum in Parkinson models of disease.
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Nizar Asadi Royal Brompton & Harefield NHS Foundation Trust
Thoracic surgery in the treatment of lung cancer
Gareth Thomas BDS, MScD, PhD, FDSRCS, FRCPath University Hospital Southampton NHS Foundation Trust.
Targeted therapies: aiming at the tumour micro-environment
Prof Samuel Janes University College London Hospitals
Nirmesh Patel Cambridge Cancer Genomics
Monitoring cancer evolution through smart genomics and liquid biopsies
Mavis Nye BCaH Mavis Nye Foundation