Mani Naghibi

St. Mark's Hospital
Consultant Gastroenterologist at St. Mark''s Hospital

Dr Mani Naghibi gained his medical degree at Guy’s Kings and St Thomas’ School of Medicine in London, where he also undertook a second intercalated degree in Anatomy and Physiology. While at University he carried out research in the topic of drug delivery to the brain. After university he completed his medical training in the London and Wessex deaneries, specialising in Gastroenterology and General Internal Medicine.

Mani undertook his sub-speciality training and research at University Hospital Southampton (UHS), supported by the National Institute of Health Research (NIHR) Biomedical Research Centre for Nutrition. His Medical Doctorate (MD) thesis was based on the use of artificial nutrition for patients with nutrition failure in the context of cancer. He has presented the results of this and other research topics at national and international conferences as well as at invited lectures.

Working with the Inflammatory Bowel Disease team at UHS, Mani was awarded the Shire Prize in innovation in Gastroenterology in 2014 for designing and implementing a web-based patient management system, which allows patients to take greater control of their health and medical treatments.

His clinical interests are supplemental and artificial nutrition, inflammatory bowel conditions, gastrointestinal endoscopy, functional bowel disorders and effects of medical treatments on quality of life. He continues his research interests into the effects of artificial nutrition in both cancer and non-cancer patients.

Before commencing his Consultant post at St Mark’s Hospital, Mani was the Specialist Registrar trainee representative for the British Society of Gastroenterology (BSG) Small Bowel and Nutrition committee, as well as the British Association for Parenteral and Enteral Nutrition (BAPEN). He is currently a committee member for the British Artificial Nutrition Survey (BANS).

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Using nutrition therapies to positively effect cancer treatment outcomes

The link between nutrition and cancer prevention, improved treatment results and quality of life is recognised widely. The means to influence these outcomes positively have been lacking in all except the most malnourished patients. We are now developing the tools to identify and nutritionally treat patients to positively influence cancer treatment tolerance, survival and burden of therapies. These tools include use of imaging to identify hidden low muscle mass, nutrients targeted at reducing inflammation, pharmaceutical agents to improve body composition and multimodal therapies to increase strength and resilience.